Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.34 |
| ▸ | GRM6 | O15303 | 5/20 | 0.33 |
| ▸ | GRM5 | P41594 | 4/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23610999 | 1.00 | GRM1 (0.41) | GRM1POLBKDM4EAPEX1TDP1 | |
| SCHEMBL18053340 | 1.00 | GRM1 (0.41) | GRM1POLBKDM4EAPEX1TDP1 | |
| SCHEMBL20382051 | 1.00 | GRM1 (0.41) | GRM1POLBKDM4EAPEX1TDP1 | |
| SCHEMBL23611095 | 1.00 | GRM1 (0.41) | GRM1POLBKDM4EAPEX1TDP1 | |
| SCHEMBL18055930 | 1.00 | GRM1 (0.41) | GRM1POLBKDM4EAPEX1TDP1 | |
| Hydrochloric Acid SCHEMBL21068146 | 0.97 | GRM1 (0.39) | GRM1POLBKDM4EAPEX1TDP1 | |
| Hydrochloric Acid SCHEMBL25179204 | 0.97 | GRM1 (0.39) | GRM1POLBKDM4EAPEX1TDP1 | |
| Hydrochloric Acid SCHEMBL21820830 | 0.91 | GRM2 (0.38) | GRM1POLBKDM4EAPEX1TDP1 | |
| SCHEMBL21986562 | 0.85 | LMNA (0.41) | GRM1POLBKDM4EAPEX1TDP1 | |
| SCHEMBL1254906 | 0.85 | LMNA (0.41) | GRM1POLBKDM4EAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362451-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| EP-3555095-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| US-11535613-B2 | Crystal form and salt form of pyridoimidazole compound and preparation method therefor | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-12-27 | — | — | US | disclosed |
| CN-110446711-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2022-02-15 | — | — | CN | disclosed |
| US-11225477-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-01-18 | — | — | US | disclosed |
| EP-3380467-B1 | HETEROCYCLIC INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-07 | — | — | EP | disclosed |
| CN-108290869-B | Heterocyclic indoles for use in influenza virus infection | 爱尔兰詹森科学公司 | 2021-05-18 | — | — | CN | disclosed |
| US-10987354-B2 | Inhibitors of influenza virus replication and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-04-27 | — | — | US | disclosed |
| US-10927118-B2 | Inhibitors of influenza virus replication and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-02-23 | — | — | US | disclosed |
| EP-3763713-A1 | CRYSTAL FORM AND SALT FORM OF PYRIDOIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2021-01-13 | — | — | EP | disclosed |
| EP-2357181-A1 | 2,4-Diaminopyrimidines as inhibitors of cell cycle kinases | Boehringer Ingelheim International GmbH (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-20110150917-A1 | Small Cationic Antimicrobial Peptides | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-06-23 | — | — | US | disclosed |
| US-20090163467-A1 | New compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090163467-A1 | New compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090163467-A1 | New compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| EP-2061886-A1 | SMALL CATIONIC ANTIMICROBIAL PEPTIDES | The University of British Columbia (CA) | 2009-05-27 | — | — | EP | disclosed |
| EP-2027107-A1 | 2, 4 -DIAMINO PYRIMIDINES AS CELL CYCLE KINASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2008151434-A1 | SMALL CATIONIC ANTIMICROBIAL PEPTIDES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008022444-A1 | SMALL CATIONIC ANTIMICROBIAL PEPTIDES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-02-28 | — | — | WO | disclosed |
| WO-2007132010-A1 | 2, 4 -DIAMINO PYRIMIDINES AS CELL CYCLE KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927118-B2 | Inhibitors of influenza virus replication and uses thereof | EIF2AK2, POLRMT, ZC3HAV1 | GRM1 4819/4885POLB 24/4885KDM4E 2023/4885 |
| US-10987354-B2 | Inhibitors of influenza virus replication and uses thereof | ZC3HAV1, MAVS, POLRMT | GRM1 4841/4885POLB 35/4885KDM4E 962/4885 |
| US-11535613-B2 | Crystal form and salt form of pyridoimidazole compound and preparation method therefor | SLC5A11, SLC39A11, CYP4F11 | GRM1 3124/4885POLB 3509/4885KDM4E 3462/4885 |
| US-11225477-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | POLRMT, EIF2AK2, POLM | GRM1 4814/4885POLB 12/4885KDM4E 1334/4885 |
| US-20090163467-A1 | New compounds | CCNA1, MKI67, CCNT1 | GRM1 1279/4885POLB 2138/4885KDM4E 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.