Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855134 | 0.86 | CNR2 (0.33) | POLB | |
| SCHEMBL14430114 | 0.80 | TP53 (0.41) | TP53NCF1CHRM3GNAI3GNAO1 | |
| SCHEMBL27432912 | 0.79 | NCF1 (0.39) | NCF1CHRM3GNAI3GNAO1GNAI1 | |
| SCHEMBL22147474 | 0.73 | NCF1 (0.38) | NCF1CHRM3GNAI3GNAO1GNAI1 | |
| SCHEMBL16732113 | 0.73 | CTSK (0.41) | — | |
| SCHEMBL11927513 | 0.73 | NCF1 (0.45) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL1813937 | 0.73 | CHRM3 (0.43) | TP53NCF1CHRM3 | |
| SCHEMBL16118851 | 0.72 | APLNR (0.35) | — | |
| SCHEMBL31678956 | 0.72 | ANPEP (0.36) | KMT2A | |
| SCHEMBL4418786 | 0.72 | CTSK (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006010079-A2 | PROCESS FOR PREPARING NARATRIPTAN HYDROCHLORIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-01-26 | — | — | WO | disclosed |