Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504375 | 0.91 | AKR1B1 (0.38) | MPIAKR1B1LMNAL3MBTL1 | |
| SCHEMBL423445 | 0.91 | AKR1B1 (0.38) | MPIAKR1B1LMNAL3MBTL1 | |
| SCHEMBL8653995 | 0.91 | AKR1B1 (0.38) | MPIAKR1B1LMNAL3MBTL1 | |
| SCHEMBL423446 | 0.91 | AKR1B1 (0.38) | MPIAKR1B1LMNAL3MBTL1 | |
| SCHEMBL8948482 | 0.91 | AKR1B1 (0.38) | MPIAKR1B1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15779291 | 0.89 | AKR1B1 (0.36) | MPIAKR1B1LMNAL3MBTL1 | |
| E968 SCHEMBL20559013 | 0.78 | LMNA (0.47) | MPIAKR1B1PGDLMNAL3MBTL1 | |
| E968 SCHEMBL31315354 | 0.78 | LMNA (0.47) | MPIAKR1B1PGDLMNAL3MBTL1 | |
| SCHEMBL5699947 | 0.78 | AKR1B1 (0.43) | AKR1B1 | |
| SCHEMBL17984952 | 0.77 | LMNA (0.46) | AKR1B1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006006757-A1 | COMPOSITION FOR LOWERING BLOOD GLUCOSE COMPRISING HEXOSE MONOPHOSPHATE | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2006-01-19 | — | — | WO | claimed |
| WO-2006006757-A1 | COMPOSITION FOR LOWERING BLOOD GLUCOSE COMPRISING HEXOSE MONOPHOSPHATE | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2006-01-19 | — | — | WO | disclosed |