SCHEMBL504375

SCHEMBL504375

O=CCCC(O)C(O)CO

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.38
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
HIF1A Q16665 1/20 0.32
MPI P34949 1/20 0.31
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL423446 1.00 AKR1B1 (0.38) AKR1B1LMNAL3MBTL1TDP1HIF1A
SCHEMBL423445 1.00 AKR1B1 (0.38) AKR1B1LMNAL3MBTL1TDP1HIF1A
SCHEMBL8653995 1.00 AKR1B1 (0.38) AKR1B1LMNAL3MBTL1TDP1HIF1A
SCHEMBL8948482 1.00 AKR1B1 (0.38) AKR1B1LMNAL3MBTL1TDP1HIF1A
Hydrochloric Acid SCHEMBL15779291 0.97 AKR1B1 (0.36) AKR1B1LMNAL3MBTL1TDP1HIF1A
Phosphoric Acid SCHEMBL5789491 0.91 MPI (0.39) AKR1B1LMNAL3MBTL1MPI
SCHEMBL5699947 0.85 AKR1B1 (0.43) AKR1B1
SCHEMBL17984936 0.85 HIF1A (0.41) AKR1B1LMNAL3MBTL1TDP1HIF1A
SCHEMBL17984952 0.85 LMNA (0.46) AKR1B1LMNAL3MBTL1TDP1PDE4A
SCHEMBL17984927 0.84 THRB (0.33) AKR1B1HIF1AMPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510470-A CONTAINS A DIDEOXYSACCHARIDE; USED WITH ZERO VALENT NICKEL AS A CATALYST FOR ENANTIOSELECTIVE HYDROCYANATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-23 US claimed
US-5484902-A HYDROCYANATION OF VINYL AROMATICS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-01-16 US claimed
CN-119907682-A Development of carbohydrate-based anti-salmonella vaccines 密西根州立大学校董会 2025-04-29 CN disclosed
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2025-04-24 US disclosed
US-12076418-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo ENGENE, INC. (CA) 2024-09-03 US disclosed
CN-117843740-A Transcription factor AcaR, gene and recombinant bacterium derived from actinoplanes, and preparation methods and applications thereof 安徽工程大学 2024-04-09 CN disclosed
CN-114728053-A Immunogenic compositions against intestinal disease and process for preparing same 印度血清研究所私人有限公司 2022-07-08 CN disclosed
US-20220133907-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2022-05-05 US disclosed
EP-3970697-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO Engene, Inc. (CA) 2022-03-23 EP disclosed
US-11167045-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo HERCULES CAPITAL, INC. 2021-11-09 US disclosed
EP-3049473-B1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO ENGENE INC (CA) 2021-09-22 EP disclosed
WO-1998053851-A1 LAFT MUTANTS OF PATHOGENIC GRAM-NEGATIVE BACTERIA UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1998-12-03 WO disclosed
EP-0876150-A1 NON-TOXIC MUTANTS OF PATHOGENIC GRAM-NEGATIVE BACTERIA UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1998-11-11 EP disclosed
CN-1172161-A Acarviosyl transferase and preparation and application thereof BAYER AG (DE) 1998-02-04 CN disclosed
WO-1997019688-A9 NON-TOXIC MUTANTS OF PATHOGENIC GRAM-NEGATIVE BACTERIA 1997-09-18 WO disclosed
WO-1997019688-A1 NON-TOXIC MUTANTS OF PATHOGENIC GRAM-NEGATIVE BACTERIA UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1997-06-05 WO disclosed
US-5510470-A CONTAINS A DIDEOXYSACCHARIDE; USED WITH ZERO VALENT NICKEL AS A CATALYST FOR ENANTIOSELECTIVE HYDROCYANATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-23 US disclosed
US-4696916-A Intravenous nutrient UNITIKA LTD. (JP) 1987-09-29 US disclosed
EP-0100382-B1 AN INTRAVENOUS NUTRIENT UNITIKA LTD. (JP) 1986-11-20 EP disclosed
EP-0100382-A1 An intravenous nutrient UNITIKA LTD. (JP) 1984-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885LMNA 1219/4885L3MBTL1 448/4885
US-11167045-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885LMNA 1219/4885L3MBTL1 448/4885
US-12076418-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885LMNA 1219/4885L3MBTL1 448/4885
US-20220133907-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885LMNA 1219/4885L3MBTL1 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.