Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5789960 | 1.00 | MAPT (0.57) | MAPTALDH1A1KDM4EPOLBCTDSP1 | |
| Ammonia Solution, Strong SCHEMBL5792939 | 0.88 | LMNA (0.54) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| Ammonia Solution, Strong SCHEMBL5792944 | 0.88 | LMNA (0.54) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| Ammonia Solution, Strong SCHEMBL5791246 | 0.87 | MAPT (0.67) | MAPTALDH1A1KDM4EPOLBCTDSP1 | |
| Ammonia Solution, Strong SCHEMBL5791250 | 0.87 | MAPT (0.67) | MAPTALDH1A1KDM4EPOLBCTDSP1 | |
| Ammonia Solution, Strong SCHEMBL5791242 | 0.87 | MAPT (0.67) | MAPTALDH1A1KDM4EPOLBCTDSP1 | |
| SCHEMBL13568996 | 0.84 | POLB (0.72) | MAPTALDH1A1KDM4EPOLBCTDSP1 | |
| Ammonia Solution, Strong SCHEMBL5789879 | 0.79 | MAPT (0.50) | MAPTALDH1A1KDM4EPOLBTDP1 | |
| Ammonia Solution, Strong SCHEMBL5789876 | 0.79 | MAPT (0.50) | MAPTALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL5789763 | 0.77 | POLB (0.48) | MAPTALDH1A1KDM4EPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000294-A1 | NOVEL DIAZENIUMDIOLATE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | claimed |
| WO-2006000294-A1 | NOVEL DIAZENIUMDIOLATE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |