Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5791250 | 1.00 | MAPT (0.67) | MAPTKMT2AMEN1ALDH1A1APOBEC3A | |
| Ammonia Solution, Strong SCHEMBL5791246 | 1.00 | MAPT (0.67) | MAPTKMT2AMEN1ALDH1A1APOBEC3A | |
| Ammonia Solution, Strong SCHEMBL5789965 | 0.87 | MAPT (0.57) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| Ammonia Solution, Strong SCHEMBL5789960 | 0.87 | MAPT (0.57) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| Ammonia Solution, Strong SCHEMBL5792939 | 0.78 | LMNA (0.54) | MAPTKMT2AALDH1A1POLBSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL5792944 | 0.78 | LMNA (0.54) | MAPTKMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5791695 | 0.72 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| Ammonia Solution, Strong SCHEMBL5789879 | 0.71 | MAPT (0.50) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL5789876 | 0.71 | MAPT (0.50) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL13568996 | 0.71 | POLB (0.72) | MAPTKMT2AMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000294-A1 | NOVEL DIAZENIUMDIOLATE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | claimed |