Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5789876 | 1.00 | MAPT (0.50) | MAPTKMT2AMEN1LMNAPKM | |
| SCHEMBL5789763 | 0.82 | POLB (0.48) | MAPTKMT2AMEN1LMNAPKM | |
| SCHEMBL5789769 | 0.82 | POLB (0.48) | MAPTKMT2AMEN1LMNAPKM | |
| Ammonia Solution, Strong SCHEMBL5789965 | 0.79 | MAPT (0.57) | MAPTKMT2AMEN1LMNAKDM4E | |
| Ammonia Solution, Strong SCHEMBL5789960 | 0.79 | MAPT (0.57) | MAPTKMT2AMEN1LMNAKDM4E | |
| SCHEMBL13569080 | 0.78 | MAPT (0.65) | MAPTKMT2AMEN1LMNAPKM | |
| Ammonia Solution, Strong SCHEMBL5792939 | 0.74 | LMNA (0.54) | MAPTKMT2ALMNAKDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL5792944 | 0.74 | LMNA (0.54) | MAPTKMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL12310043 | 0.73 | KDM4E (0.66) | MAPTKMT2AMEN1LMNAKDM4E | |
| SCHEMBL4076943 | 0.73 | POLB (0.60) | MAPTKMT2AMEN1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000294-A1 | NOVEL DIAZENIUMDIOLATE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | claimed |
| WO-2006000294-A1 | NOVEL DIAZENIUMDIOLATE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |