Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | USP19 | O94966 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534136 | 0.78 | MEN1 (0.38) | MEN1CYP2C19KMT2AHTTUSP19 | |
| SCHEMBL2535973 | 0.78 | EPHX1 (0.39) | MEN1CYP2C19KMT2AHTTUSP19 | |
| SCHEMBL16148375 | 0.75 | MEN1 (0.33) | MEN1CYP2C19KMT2AHTTUSP19 | |
| SCHEMBL2936663 | 0.75 | MEN1 (0.33) | MEN1CYP2C19KMT2AHTT | |
| SCHEMBL27796397 | 0.75 | ALDH1A1 (0.38) | MEN1CYP2C19KMT2AHTTUSP19 | |
| SCHEMBL5791987 | 0.75 | CTSD (0.39) | MEN1KMT2AUSP19 | |
| SCHEMBL8322242 | 0.75 | CHRNB2 (0.37) | MEN1CYP2C19KMT2ACHRNB2CHRNA4 | |
| SCHEMBL2930360 | 0.74 | HTT (0.33) | MEN1CYP2C19KMT2AHTTUSP19 | |
| SCHEMBL2934366 | 0.73 | SRC (0.46) | MEN1CYP2C19KMT2AHTTUSP19 | |
| SCHEMBL20825893 | 0.72 | ALDH1A1 (0.39) | HTTUSP19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636224-A2 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE | Prosidion Limited (GB) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004104001-A2 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE | PROSIDION LIMITED (GB) | 2004-12-02 | — | — | WO | disclosed |