Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 10/20 | 0.52 |
| ▸ | DRD3 | P35462 | 7/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808854 | 1.00 | HTR1A (0.60) | HTR1ADRD2DRD3DRD4DRD1 | |
| SCHEMBL5806321 | 0.88 | DRD2 (0.62) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5805982 | 0.79 | HTR1A (0.68) | HTR1ADRD2DRD3DRD4DRD1 | |
| SCHEMBL5793240 | 0.79 | HTR1A (0.68) | HTR1ADRD2DRD3DRD4DRD1 | |
| SCHEMBL5805984 | 0.79 | HTR1A (0.68) | HTR1ADRD2DRD3DRD4DRD1 | |
| SCHEMBL5807853 | 0.79 | HTR1A (0.49) | HTR1ADRD2DRD3DRD4DRD1 | |
| SCHEMBL5806623 | 0.77 | HTR1A (0.55) | HTR1ADRD2DRD3DRD4DRD1 | |
| SCHEMBL31558065 | 0.77 | HTR1A (1.00) | HTR1ADRD2DRD3DRD4DRD1 | |
| SCHEMBL9359278 | 0.77 | HTR1A (1.00) | HTR1ADRD2DRD3DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL29064041 | 0.75 | HTR1A (0.97) | HTR1ADRD2DRD3DRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016245-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | disclosed |
| WO-2005089515-A9 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | BRIGHAM & WOMENS HOSPITAL (US) | 2006-01-26 | — | — | WO | disclosed |