Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.54 |
| ▸ | KAT7 | O95251 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791461 | 0.86 | KMT2A (0.49) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL5791116 | 0.85 | ACKR3 (0.55) | ACKR3KAT7KAT8USP30KMT2A | |
| SCHEMBL5792816 | 0.82 | CCR2 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL3765452 | 0.77 | ACKR3 (0.60) | ACKR3USP30KMT2AMEN1ALDH1A1 | |
| SCHEMBL13056746 | 0.77 | ACKR3 (0.60) | ACKR3USP30KMT2AMEN1ALDH1A1 | |
| SCHEMBL3448188 | 0.77 | KDM4E (0.69) | ACKR3KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3448190 | 0.77 | KDM4E (0.69) | ACKR3KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL2070349 | 0.77 | PPARA (0.61) | ACKR3CNR1CNR2CYP2C9 | |
| SCHEMBL4847812 | 0.76 | CCR2 (0.57) | KMT2AMEN1KDM4EPKM | |
| SCHEMBL2069204 | 0.75 | CHEK2 (0.59) | ACKR3KAT7KAT8KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |