Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791461 | 0.85 | KMT2A (0.49) | CCR2DRD2DRD3DRD4KMT2A | |
| SCHEMBL5792050 | 0.84 | DRD2 (0.50) | CCR2DRD2DRD3DRD4KMT2A | |
| SCHEMBL5790711 | 0.82 | ACKR3 (0.54) | KMT2AALDH1A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL5791504 | 0.78 | SLC2A1 (0.44) | CYP2D6CACNA1HKCNH2KMT2ATP53 | |
| SCHEMBL5792117 | 0.74 | GABRA5 (0.43) | KCNH2 | |
| SCHEMBL27684193 | 0.74 | NPC1 (0.57) | CCR2KMT2APOLBMEN1 | |
| SCHEMBL589624 | 0.72 | CHRM1 (0.54) | CCR2POLB | |
| SCHEMBL11532875 | 0.71 | CYP2D6 (0.52) | CCR2CYP2D6CACNA1HKCNH2DRD2 | |
| SCHEMBL5791107 | 0.69 | KMT2A (0.47) | CYP2D6CACNA1HKCNH2KMT2AALDH1A1 | |
| SCHEMBL5792775 | 0.69 | DRD2 (0.45) | CCR2KCNH2DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |