Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | FPR3 | P25089 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | KAT7 | O95251 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790711 | 0.85 | ACKR3 (0.54) | ACKR3KDM4EPKMCYP2C9KDM1A | |
| SCHEMBL5792817 | 0.85 | DRD2 (0.46) | KDM4EDRD2DRD4DRD3KMT2A | |
| SCHEMBL5794048 | 0.85 | ACKR3 (0.51) | ACKR3KDM4EPKMFPR3FPR2 | |
| SCHEMBL20528788 | 0.82 | ACKR3 (0.53) | ACKR3KDM4EPKMFPR3FPR2 | |
| SCHEMBL20528789 | 0.82 | ACKR3 (0.53) | ACKR3KDM4EPKMFPR3FPR2 | |
| SCHEMBL20528900 | 0.81 | ACKR3 (0.52) | ACKR3KDM4EPKMFPR3FPR2 | |
| SCHEMBL20528901 | 0.81 | ACKR3 (0.52) | ACKR3KDM4EPKMFPR3FPR2 | |
| SCHEMBL20528743 | 0.81 | USP30 (0.48) | ACKR3KDM4EPKMFPR3FPR2 | |
| SCHEMBL20528741 | 0.81 | USP30 (0.48) | ACKR3KDM4EPKMFPR3FPR2 | |
| SCHEMBL13056746 | 0.80 | ACKR3 (0.60) | ACKR3KDM4EPKMCYP2C9KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |