Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | C1R | P00736 | 7/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792385 | 0.81 | PKM (0.83) | MEN1KMT2AC1RPKMNPC1 | |
| SCHEMBL914103 | 0.80 | C1R (0.65) | MEN1KMT2AC1RNPC1ELANE | |
| SCHEMBL5793015 | 0.78 | KMT2A (0.63) | MEN1KMT2AC1RPKMNPC1 | |
| SCHEMBL17554028 | 0.78 | C1R (0.62) | MEN1KMT2AC1RNPC1MAPT | |
| SCHEMBL5371767 | 0.77 | C1R (0.69) | MEN1KMT2AC1RNPC1MAPT | |
| SCHEMBL913682 | 0.77 | C1R (0.68) | MEN1KMT2AC1RPKMNPC1 | |
| SCHEMBL914361 | 0.75 | C1R (0.74) | MEN1KMT2AC1RNPC1MAPT | |
| SCHEMBL22272031 | 0.74 | MEN1 (1.00) | MEN1KMT2AC1RPKMMAPT | |
| SCHEMBL914778 | 0.74 | APEX1 (0.63) | MEN1KMT2AC1RPKMNPC1 | |
| SCHEMBL5793545 | 0.73 | C1R (0.76) | MEN1KMT2AC1RNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |