Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.83 |
| ▸ | CD74 | P04233 | 1/20 | 0.66 |
| ▸ | MIF | P14174 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | C1R | P00736 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17254720 | 0.89 | CD74 (0.67) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL5921134 | 0.83 | C1R (0.68) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL6565958 | 0.83 | POLB (0.70) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL5790792 | 0.81 | MEN1 (0.59) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL6565635 | 0.81 | POLB (0.67) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL17254759 | 0.80 | MAPT (0.60) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL5921400 | 0.80 | ALDH1A1 (0.69) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL5921076 | 0.80 | C1R (0.65) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL258516 | 0.80 | KMT2A (0.62) | PKMCD74MIFPOLBMAPT | |
| SCHEMBL2757824 | 0.80 | CD74 (1.00) | PKMCD74MIFPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |