Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243073 | 0.81 | KDM4E (0.35) | TDP1CYP3A4KDM4ELMNAPOLB | |
| SCHEMBL25246032 | 0.80 | POLB (0.55) | ESR1TDP1KDM4ELMNAPOLB | |
| Boric Acid SCHEMBL32681745 | 0.76 | POLB (0.50) | ESR1TDP1KDM4ELMNAPOLB | |
| SCHEMBL282481 | 0.74 | KDM4E (0.63) | TTRESR1PTPN1TDP1KDM4E | |
| SCHEMBL4239126 | 0.74 | POLB (0.40) | TTRTDP1TSHRKDM4ELMNA | |
| SCHEMBL22887516 | 0.73 | LMNA (0.46) | TDP1CYP3A4TSHRLMNAPOLB | |
| SCHEMBL2534978 | 0.72 | CES2 (0.48) | ESR1PTPN1PTPN2KDM4ELMNA | |
| SCHEMBL3062001 | 0.72 | TPMT (0.46) | TSHRPOLBGAA | |
| SCHEMBL26965117 | 0.72 | TPMT (0.46) | TDP1KDM4E | |
| SCHEMBL295796 | 0.72 | ALDH1A1 (0.40) | ESR1TDP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057687-A1 | METHODS FOR PREPARING DOXORUBICIN DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | claimed |
| WO-2003057896-A1 | METHODS FOR PREPARING ANTHRACYCLINONE DERIVATIVES AND ANTHRACYCLINONE DERIVATIVES PER SE | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | claimed |
| WO-2006012277-A2 | BIOCATALYTIC PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED PRAMIPEXOLE | AMR TECHNOLOGY, INC. (US) | 2006-02-02 | — | — | WO | disclosed |
| WO-2003057896-A1 | METHODS FOR PREPARING ANTHRACYCLINONE DERIVATIVES AND ANTHRACYCLINONE DERIVATIVES PER SE | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| WO-2003057687-A1 | METHODS FOR PREPARING DOXORUBICIN DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | disclosed |