Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 3/20 | 0.58 |
| ▸ | KLK7 | P49862 | 10/20 | 0.58 |
| ▸ | KLK14 | Q9P0G3 | 10/20 | 0.58 |
| ▸ | KLK5 | Q9Y337 | 10/20 | 0.58 |
| ▸ | CTSG | P08311 | 8/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTRC | Q99895 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793545 | 0.77 | C1R (0.76) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL5790698 | 0.76 | C1R (0.72) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL692226 | 0.75 | C1R (1.00) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL30366271 | 0.75 | C1R (1.00) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL18353427 | 0.73 | KLK7 (1.00) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL914093 | 0.72 | C1R (0.66) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL5387023 | 0.72 | C1R (0.66) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL5794442 | 0.72 | ELANE (0.71) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL914380 | 0.72 | C1R (0.70) | C1RKLK7KLK14KLK5CTSG | |
| SCHEMBL18352894 | 0.70 | KLK7 (1.00) | C1RKLK7KLK14KLK5CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |