Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454105 | 1.00 | POLB (0.69) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL1746215 | 0.88 | MAPT (0.59) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL6518219 | 0.85 | POLB (0.60) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL9556012 | 0.84 | POLB (0.50) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL2868807 | 0.81 | HSD17B10 (0.47) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL2115617 | 0.81 | MAPT (1.00) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL9554515 | 0.81 | MAPT (1.00) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL7269730 | 0.79 | HSD17B10 (0.61) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL6313528 | 0.79 | POLB (0.60) | POLBL3MBTL1HSD17B10KMT2AMAPT | |
| SCHEMBL10536673 | 0.78 | ALDH1A1 (0.68) | POLBL3MBTL1HSD17B10KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006010920-A1 | SOLUBLE POLYPEPTIDE | ISIS INNOVATION LIMITED (GB) | 2006-02-02 | — | — | WO | disclosed |
| US-20050214894-A1 | High throughput assay | ISIS INNOVATION LIMITED (GB) | 2005-09-29 | — | — | US | disclosed |