Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454105 | 0.85 | POLB (0.69) | POLBKMT2AMEN1TDP1SLC7A5 | |
| SCHEMBL5791501 | 0.85 | POLB (0.69) | POLBKMT2AMEN1TDP1SLC7A5 | |
| SCHEMBL592660 | 0.78 | POLB (0.64) | POLBKMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL5010177 | 0.78 | ALDH1A1 (0.77) | POLBKMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL112098 | 0.78 | ALDH1A1 (0.77) | POLBKMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL17114021 | 0.77 | POLB (0.71) | POLBKMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL6692611 | 0.76 | POLB (1.00) | POLBKMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL11463170 | 0.76 | POLB (1.00) | POLBKMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL1746215 | 0.75 | MAPT (0.59) | POLBKMT2AMEN1TDP1SLC7A5 | |
| SCHEMBL490650 | 0.74 | SLC7A5 (0.67) | POLBSLC7A5CA2CAMK2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050214894-A1 | High throughput assay | ISIS INNOVATION LIMITED (GB) | 2005-09-29 | — | — | US | disclosed |