Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ATF4 | P18848 | 1/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803633 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2GRIN1GRIN2BL3MBTL1KMT2A | |
| SCHEMBL4577513 | 0.85 | CA12 (0.53) | GRIN1GRIN2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL9444298 | 0.79 | POLB (0.51) | L3MBTL1POLBALDH1A1MAPTNPSR1 | |
| SCHEMBL20989099 | 0.79 | ATF4 (0.69) | SMN1; SMN2GRIN1GRIN2BL3MBTL1KMT2A | |
| SCHEMBL4577835 | 0.76 | FAAH (0.53) | GRIN1GRIN2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL4591294 | 0.75 | GRIN1 (0.51) | GRIN1GRIN2BKMT2AMEN1POLB | |
| SCHEMBL4577312 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2GRIN1GRIN2BKMT2AMEN1 | |
| SCHEMBL4591719 | 0.75 | MEN1 (0.55) | SMN1; SMN2L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4771631 | 0.75 | GPR119 (0.59) | — | |
| SCHEMBL19692508 | 0.73 | ATF4 (0.70) | SMN1; SMN2L3MBTL1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006010968-A1 | NEW ARYLOXY ACETIC ACID AMIDE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | claimed |