Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790213 | 0.90 | PKM (0.48) | TACR1PKMIDO1KIF11 | |
| SCHEMBL5793858 | 0.88 | CHRNB2 (0.47) | IDO1KMT2AKIF11LMNAMAPK1 | |
| SCHEMBL5794403 | 0.86 | TACR1 (0.43) | TACR1IDO1KMT2AKDM4ELMNA | |
| SCHEMBL5792856 | 0.86 | SLC1A3 (0.44) | TACR1IDO1KMT2AKIF11KDM4E | |
| SCHEMBL5794077 | 0.85 | TACR1 (0.47) | TACR1 | |
| SCHEMBL5790217 | 0.83 | TACR1 (0.57) | TACR1IDO1 | |
| SCHEMBL5793923 | 0.82 | IDO1 (0.44) | IDO1ALDH1A1 | |
| SCHEMBL5790274 | 0.80 | IDO1 (0.45) | TACR1IDO1KIF11KDM4ELMNA | |
| SCHEMBL5792062 | 0.80 | TACR1 (0.48) | TACR1IDO1KMT2A | |
| SCHEMBL5791679 | 0.80 | CHRM3 (0.39) | TACR1IDO1KMT2AKIF11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006014942-A1 | ARYLOXYALKYLAMINE NK-1/SSRI INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-09 | — | — | WO | claimed |