Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CASR | P41180 | 4/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5792092 | 0.82 | GHSR (0.55) | GHSRCYP2D6CASRSMN1; SMN2KCNH2 | |
| SCHEMBL5791447 | 0.82 | CYP2D6 (0.53) | CYP2D6GRIN1GRIN2BPKMKDM4E | |
| SCHEMBL5794704 | 0.79 | CYP2D6 (0.55) | GHSRCYP2D6CASRGRIN1GRIN2B | |
| SCHEMBL5792841 | 0.77 | GHSR (0.65) | GHSRCYP2D6CASRCYP3A4KCNH2 | |
| SCHEMBL5819936 | 0.76 | GHSR (0.58) | GHSRCYP2D6CASRCYP3A4KCNH2 | |
| SCHEMBL5791517 | 0.74 | GHSR (0.75) | GHSRCYP2D6CASRALDH1A1HSD17B10 | |
| SCHEMBL12788321 | 0.73 | POLB (0.59) | GHSRCYP2D6KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6308155 | 0.73 | BRD4 (0.47) | GHSRCYP2D6KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5823984 | 0.72 | CYP2D6 (0.76) | GHSRCYP2D6CYP3A4KCNH2 | |
| SCHEMBL5750922 | 0.72 | CASR (0.83) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |