Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791739 | 0.91 | DRD2 (0.42) | DRD2DRD4DRD3NPC1ALDH1A1 | |
| SCHEMBL5794060 | 0.88 | DRD2 (0.44) | DRD2DRD4DRD3NPC1ALDH1A1 | |
| SCHEMBL5791052 | 0.82 | KMT2A (0.47) | DRD2DRD4DRD3NPC1ALDH1A1 | |
| SCHEMBL5792817 | 0.81 | DRD2 (0.46) | DRD2DRD4DRD3NPC1ALDH1A1 | |
| SCHEMBL5793066 | 0.77 | DRD2 (0.41) | DRD2DRD4DRD3NPC1ALDH1A1 | |
| SCHEMBL5794048 | 0.76 | ACKR3 (0.51) | DRD2DRD4DRD3KMT2AKDM4E | |
| SCHEMBL20528789 | 0.73 | ACKR3 (0.53) | DRD2DRD4DRD3NPC1ALDH1A1 | |
| SCHEMBL20528788 | 0.73 | ACKR3 (0.53) | DRD2DRD4DRD3NPC1ALDH1A1 | |
| SCHEMBL20528901 | 0.73 | ACKR3 (0.52) | DRD2DRD4DRD3NPC1ALDH1A1 | |
| SCHEMBL20528900 | 0.73 | ACKR3 (0.52) | DRD2DRD4DRD3NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |