Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | BCL3 | P20749 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528741 | 0.88 | USP30 (0.48) | KMT2ADRD2DRD4DRD3 | |
| SCHEMBL20528743 | 0.88 | USP30 (0.48) | KMT2ADRD2DRD4DRD3 | |
| SCHEMBL5791739 | 0.84 | DRD2 (0.42) | KMT2ANPC1DRD2DRD4DRD3 | |
| SCHEMBL5794060 | 0.83 | DRD2 (0.44) | KMT2ANPC1DRD2DRD4DRD3 | |
| SCHEMBL5792123 | 0.82 | DRD2 (0.44) | KMT2ANPC1DRD2DRD4DRD3 | |
| SCHEMBL14720615 | 0.82 | DRD2 (0.50) | KMT2ANPC1RAB9ADRD2DRD4 | |
| SCHEMBL20528901 | 0.78 | ACKR3 (0.52) | KMT2ANPC1DRD2DRD4DRD3 | |
| SCHEMBL20528900 | 0.78 | ACKR3 (0.52) | KMT2ANPC1DRD2DRD4DRD3 | |
| SCHEMBL5792817 | 0.78 | DRD2 (0.46) | KMT2ANPC1DRD2DRD4DRD3 | |
| SCHEMBL10326251 | 0.75 | DRD2 (0.43) | KMT2ANPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |