SCHEMBL5792503

SCHEMBL5792503

CC1[C@H](C(N)=O)OC(=O)N1c1cc(F)c2c(c1)oc(=O)n2C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 3/20 0.32
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3041105 0.91 FADS1 (0.33) FADS1
SCHEMBL6671524 0.86 FADS1 (0.31) FADS1
SCHEMBL6674056 0.79 USP2 (0.34) FADS1
SCHEMBL3048219 0.77 FADS1 (0.32) FADS1
SCHEMBL3043366 0.77 FADS1 (0.32) FADS1
SCHEMBL3029175 0.76 MAOA (0.55) MAOA
SCHEMBL6691654 0.72 MAOA (0.35) FADS1MAOA
SCHEMBL6688290 0.71 MAOA (0.35) FADS1MAOA
SCHEMBL6674004 0.70 MAOA (0.44) MAOA
SCHEMBL3045011 0.70 MAOA (0.44) MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1478629-B1 N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS PHARMACIA & UPJOHN CO LLC (US) 2006-10-11 EP claimed