Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL15272602 | 0.99 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Alcohol SCHEMBL14358226 | 0.99 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL117978 | 0.97 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL29873336 | 0.97 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL119627 | 0.96 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL29873001 | 0.96 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Alcohol SCHEMBL579347 | 0.94 | PTPN1 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL14763888 | 0.91 | PTPN1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL29602123 | 0.91 | PTPN1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL117401 | 0.91 | PTPN1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115721567-A | Thermal wet tissue and preparation method thereof | 芜湖悠派护理用品科技股份有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-111962292-A | Spontaneous heating material body and spontaneous heating activated carbon non-woven fabric hair cap | 上海创始实业（集团）有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-104887581-B | A kind of oral care composition and preparation method thereof | 云南天美天康生物科技有限公司 | 2018-02-23 | — | — | CN | claimed |
| EP-2742983-B1 | Method for isolating fragrance and flavour compounds | SYMRISE AG (DE) | 2017-08-23 | — | — | EP | claimed |
| CN-105473002-A | 1H-PYRROLE-2,4-DICARBONYL-DERIVATIVES AND THEIR USE AS FLAVORING AGENTS | FRESENIUS KABI DE GMBH | 2016-04-06 | — | — | CN | claimed |
| EP-2742983-A1 | Method for isolating fragrance and flavour compounds | Symrise AG (DE) | 2014-06-18 | — | — | EP | claimed |
| US-20140113971-A1 | Topical NSAID Compositions Having Sensate Component | ZHANG JOANNA (US) | 2014-04-24 | — | — | US | claimed |
| US-20110237674-A1 | TOPICAL NSAID COMPOSITIONS HAVING SENSATE COMPONENT | NOVARTIS AG (CH) | 2011-09-29 | — | — | US | claimed |
| EP-2349248-A2 | TOPICAL NSAID COMPOSITIONS HAVING SENSATE COMPONENT | Novartis AG (CH) | 2011-08-03 | — | — | EP | claimed |
| WO-2010045415-A2 | TOPICAL NSAID COMPOSITIONS HAVING SENSATE COMPONENT | NOVARTIS AG (CH) | 2010-04-22 | — | — | WO | claimed |
| EP-0977554-B1 | CONFECTIONERY COMPOSITIONS | PROCTER & GAMBLE (US) | 2004-06-16 | — | — | EP | claimed |
| EP-0977553-B1 | THROAT SOOTHING COMPOSITIONS | PROCTER & GAMBLE (US) | 2003-09-10 | — | — | EP | claimed |
| US-6432441-B1 | ENCAPSULATION OF ANALGESICS, EXPECTORANTS OR ANTITUSSIVE AGENTS WITHIN PHOSPHATIDES TO PROLONG DRUG DELIVERY | THE PROCTER & GAMBLE COMPANY | 2002-08-13 | — | — | US | claimed |
| US-6306429-B1 | THROAT DROPS SUITABLE FOR RELIEF OF COUGH AND COLD SYMPTOMS | THE PROCTER & GAMBLE COMPANY | 2001-10-23 | — | — | US | claimed |
| EP-0977554-A1 | CONFECTIONERY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-02-09 | — | — | EP | claimed |
| EP-0977553-A1 | THROAT SOOTHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-02-09 | — | — | EP | claimed |
| WO-1998047483-A1 | CONFECTIONERY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-29 | — | — | WO | claimed |
| WO-1998047482-A1 | THROAT SOOTHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-29 | — | — | WO | claimed |
| EP-0837862-A1 | WARMING COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-29 | — | — | EP | claimed |
| WO-1997002273-A1 | WARMING COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237674-A1 | TOPICAL NSAID COMPOSITIONS HAVING SENSATE COMPONENT | TRPA1, TRPV1, PTGES | CYP1A2 538/4885CYP3A4 897/4885CYP2C9 425/4885 |
| US-20140113971-A1 | Topical NSAID Compositions Having Sensate Component | TRPA1, TRPV1, PTGES | CYP1A2 538/4885CYP3A4 897/4885CYP2C9 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.