Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29873001 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL29873336 | 0.98 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL117978 | 0.98 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Alcohol SCHEMBL14358226 | 0.97 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Alcohol SCHEMBL579289 | 0.96 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL14763888 | 0.95 | PTPN1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL29602123 | 0.95 | PTPN1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL117401 | 0.95 | PTPN1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Alcohol SCHEMBL15272602 | 0.94 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Hydrochloric Acid SCHEMBL28876397 | 0.94 | TAAR1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3453364-B1 | HEAT GENERATOR | KOBAYASHI PHARMACEUTICAL CO LTD (JP) | 2022-08-24 | — | — | EP | claimed |
| EP-3348242-B1 | HEATING COMPRESS | KOBAYASHI PHARMACEUTICAL CO LTD (JP) | 2022-06-29 | — | — | EP | claimed |
| EP-3569671-B1 | METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2022-06-22 | — | — | EP | claimed |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-05-31 | — | — | US | claimed |
| CN-110168038-B | Methyl menthol derivative and cold sensate composition containing same | 高砂香料工业株式会社 | 2022-05-27 | — | — | CN | claimed |
| US-11241331-B2 | Heating compress | KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) | 2022-02-08 | — | — | US | claimed |
| US-11236042-B2 | Methylmenthol derivative and cool-sensation imparter composition containing same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-02-01 | — | — | US | claimed |
| CN-108289754-B | Heating appliance | 小林制药株式会社 | 2021-09-07 | — | — | CN | claimed |
| US-10993833-B2 | Heat generator | KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) | 2021-05-04 | — | — | US | claimed |
| US-10980665-B2 | Heat generator | KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) | 2021-04-20 | — | — | US | claimed |
| US-20080253973-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | FOAMIX LTD. (IL) | 2008-10-16 | — | — | US | claimed |
| EP-1973422-A1 | COMPOSITIONS PROVIDING A HEATING SENSATION FOR ORAL OR DERMAL DELIVERY | Cadbury Adams USA LLC (US) | 2008-10-01 | — | — | EP | claimed |
| EP-1912516-A2 | SENSATION MASKING COMPOSITION | Takasago International Corporation (USA) (US) | 2008-04-23 | — | — | EP | claimed |
| EP-1885275-A1 | TOPICAL WARMING COMPOSITION | Takasago International Corporation (USA) (US) | 2008-02-13 | — | — | EP | claimed |
| WO-2007126430-A1 | COMPOSITIONS PROVIDING A HEATING SENSATION FOR ORAL OR DERMAL DELIVERY | CADBURY ADAMS USA LLC (US) | 2007-11-08 | — | — | WO | claimed |
| US-20070148103-A1 | Compositions providing a heating sensation for oral or dermal delivery | CADBURY ADAMS USA, LLC. | 2007-06-28 | — | — | US | claimed |
| WO-2007022056-A2 | SENSATION MASKING COMPOSITION | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070036733-A1 | Sensation masking composition | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2007-02-15 | — | — | US | claimed |
| WO-2006130710-A1 | TOPICAL WARMING COMPOSITION | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2006-12-07 | — | — | WO | claimed |
| US-20060269500-A1 | Topical warming composition | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2006-11-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070148103-A1 | Compositions providing a heating sensation for oral or dermal delivery | TAS2R8, TAS2R60, TAS2R20 | CYP1A2 2289/4885CYP3A4 3472/4885CYP2C9 2003/4885 |
| US-20070036733-A1 | Sensation masking composition | TRPA1, TRPV1, TRPM5 | CYP1A2 1951/4885CYP3A4 1873/4885CYP2C9 2299/4885 |
| US-20060269500-A1 | Topical warming composition | CUTA, NACA, LSM14A | CYP1A2 1601/4885CYP3A4 3092/4885CYP2C9 2076/4885 |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | CNR2, ADRB2, TRPA1 | CYP1A2 1421/4885CYP3A4 4632/4885CYP2C9 3242/4885 |
| US-20080253973-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | TRPA1, GPR35, TRPV1 | CYP1A2 1644/4885CYP3A4 2868/4885CYP2C9 2547/4885 |
| US-11236042-B2 | Methylmenthol derivative and cool-sensation imparter composition containing same | TRPM8, TRPM4, TRPM2 | CYP1A2 1298/4885CYP3A4 1992/4885CYP2C9 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.