Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752601 | 0.75 | MIF (0.51) | MIFGABRA1KDM4ERAB9ANPC1 | |
| SCHEMBL5793081 | 0.74 | CYP11B2 (0.44) | KDM4ERAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL27002480 | 0.72 | ALDH1A1 (0.37) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL22316605 | 0.70 | MIF (0.41) | MIFGABRA1KDM4ERAB9ANPC1 | |
| SCHEMBL12485711 | 0.70 | LIMK1 (0.57) | MIFGABRA1KDM4ERAB9ANPC1 | |
| SCHEMBL31388718 | 0.70 | GPR3 (0.46) | KDM4ERAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5335450 | 0.69 | MIF (0.49) | MIFGABRA1KDM4ERAB9ANPC1 | |
| SCHEMBL13837353 | 0.69 | MIF (0.49) | MIFGABRA1KDM4ERAB9ANPC1 | |
| SCHEMBL23261474 | 0.68 | GPR3 (0.44) | KDM4EMAPTSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL11331315 | 0.68 | LIMK1 (0.46) | GABRA1KDM4ERAB9AMAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006018544-A1 | COMPOSITION CONTAINING A THIOPHENIC OR BENZOTHIOPHENIC COMPOUND AND EXHIBITING A PUMP NORA INHIBITING ACTIVITY | UNIVERSITE CLAUDE BERNARD LYON I (FR) | 2006-02-23 | — | — | WO | claimed |
| WO-2006018544-A1 | COMPOSITION CONTAINING A THIOPHENIC OR BENZOTHIOPHENIC COMPOUND AND EXHIBITING A PUMP NORA INHIBITING ACTIVITY | UNIVERSITE CLAUDE BERNARD LYON I (FR) | 2006-02-23 | — | — | WO | disclosed |