Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793106 | 1.00 | CNR2 (0.47) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL27593728 | 0.81 | CNR2 (0.50) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL4404077 | 0.77 | CNR2 (0.64) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL5793264 | 0.76 | CNR2 (0.46) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL5357601 | 0.75 | CNR2 (0.54) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL287165 | 0.75 | RAB9A (0.56) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL349832 | 0.74 | CNR2 (0.56) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL28492272 | 0.74 | CNR2 (0.53) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL970997 | 0.74 | CNR2 (0.53) | CNR2RAB9AMAPTMEN1TP53 | |
| SCHEMBL22664584 | 0.74 | RAB9A (0.55) | CNR2RAB9AMAPTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033551-A1 | CASPASE INHIBITORS CONTAINING DICARBONYLAMINO-ISOXAZOLINE | LG LIFE SCIENCES LTD. (KR) | 2006-03-30 | — | — | WO | disclosed |