Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593728 | 0.80 | CNR2 (0.50) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL5793106 | 0.76 | CNR2 (0.47) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL5793101 | 0.76 | CNR2 (0.47) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL4404077 | 0.76 | CNR2 (0.64) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL5793266 | 0.75 | CNR2 (0.43) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL287165 | 0.74 | RAB9A (0.56) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL5357601 | 0.74 | CNR2 (0.54) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL8978021 | 0.73 | NR4A1 (0.53) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL29883614 | 0.73 | NR4A1 (0.53) | CNR2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL22664584 | 0.73 | RAB9A (0.55) | CNR2ALDH1A1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033551-A1 | CASPASE INHIBITORS CONTAINING DICARBONYLAMINO-ISOXAZOLINE | LG LIFE SCIENCES LTD. (KR) | 2006-03-30 | — | — | WO | disclosed |