Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | FABP3 | P05413 | 5/20 | 0.50 |
| ▸ | FABP4 | P15090 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166011 | 0.86 | ALDH1A1 (0.47) | ALDH1A1FABP3FABP4KMT2AMEN1 | |
| SCHEMBL5820920 | 0.83 | FABP3 (0.54) | ALDH1A1FABP3FABP4FABP5AKR1C2 | |
| SCHEMBL15057790 | 0.82 | MEN1 (0.50) | ALDH1A1FABP3FABP4KMT2AMEN1 | |
| SCHEMBL30848253 | 0.81 | ALDH1A1 (0.53) | ALDH1A1FABP4KMT2AMEN1MAPT | |
| SCHEMBL2462914 | 0.80 | MEN1 (0.60) | ALDH1A1FABP3FABP4KMT2AMEN1 | |
| SCHEMBL15060463 | 0.80 | CASP7 (0.53) | ALDH1A1FABP4KMT2AMEN1MAPT | |
| SCHEMBL3824310 | 0.80 | ALDH1A1 (0.51) | ALDH1A1FABP4KMT2AMEN1MAPT | |
| SCHEMBL18980394 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL28992361 | 0.76 | KMT2A (0.55) | ALDH1A1FABP3FABP4KMT2AMEN1 | |
| SCHEMBL31037493 | 0.76 | FABP3 (0.68) | ALDH1A1FABP3FABP4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006022955-A2 | TOPOISOMERASE INHIBITORS | PROPHARMACON, INC. (US) | 2006-03-02 | — | — | WO | disclosed |