Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.54 |
| ▸ | FABP4 | P15090 | 7/20 | 0.54 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 2/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332581 | 0.87 | ALDH1A1 (0.57) | FABP4ALDH1A1WDR5ALOX15HNF4A | |
| SCHEMBL28992361 | 0.85 | KMT2A (0.55) | FABP3FABP4FABP5ALDH1A1TSHR | |
| SCHEMBL7528413 | 0.84 | FABP3 (0.68) | FABP3FABP4FABP5ALDH1A1AKR1C2 | |
| SCHEMBL31037493 | 0.84 | FABP3 (0.68) | FABP3FABP4FABP5ALDH1A1AKR1C2 | |
| SCHEMBL28166011 | 0.83 | ALDH1A1 (0.47) | FABP3FABP4FABP5ALDH1A1AKR1C2 | |
| SCHEMBL5793392 | 0.83 | ALDH1A1 (0.50) | FABP3FABP4FABP5ALDH1A1AKR1C2 | |
| SCHEMBL901069 | 0.83 | ACMSD (0.61) | ALDH1A1WDR5ALOX15HNF4AACMSD | |
| SCHEMBL9756514 | 0.78 | WDR5 (0.47) | FABP3FABP4FABP5ALDH1A1WDR5 | |
| SCHEMBL9152464 | 0.78 | ACMSD (0.55) | ALDH1A1WDR5ALOX15HNF4AACMSD | |
| SCHEMBL12006684 | 0.78 | HNF4A (0.55) | FABP3FABP4FABP5ALDH1A1AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006022955-A2 | TOPOISOMERASE INHIBITORS | PROPHARMACON, INC. (US) | 2006-03-02 | — | — | WO | disclosed |