Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP4 | P49662 | 1/20 | 0.47 |
| ▸ | CASP5 | P51878 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792620 | 0.89 | CASP1 (0.61) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5792740 | 0.81 | CRHBP (0.68) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5791838 | 0.80 | CRHBP (0.62) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5792121 | 0.79 | CRHBP (0.61) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5792508 | 0.74 | CRHBP (0.60) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5788914 | 0.74 | HRH4 (0.73) | CRHBPCRHR2SMN1; SMN2HRH4HRH3 | |
| SCHEMBL5788921 | 0.73 | CRHBP (0.96) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL23377845 | 0.73 | HRH3 (0.62) | HRH3HTR2AHTR2CHTR7SIGMAR1 | |
| SCHEMBL5790907 | 0.72 | CRHBP (0.57) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5792439 | 0.72 | CRHBP (0.57) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | claimed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | disclosed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |