Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792508 | 0.95 | CRHBP (0.60) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5792740 | 0.88 | CRHBP (0.68) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5792121 | 0.86 | CRHBP (0.61) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5792620 | 0.82 | CASP1 (0.61) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL11981518 | 0.80 | SORD (0.57) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5788914 | 0.80 | HRH4 (0.73) | CRHBPCRHR2SMN1; SMN2HRH4MAPT | |
| SCHEMBL5793401 | 0.80 | CRHBP (0.53) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5788921 | 0.80 | CRHBP (0.96) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5790907 | 0.78 | CRHBP (0.57) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 | |
| SCHEMBL5792439 | 0.78 | CRHBP (0.57) | CRHBPCRHR2SMN1; SMN2EHMT2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | claimed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | disclosed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |