SCHEMBL579354

SCHEMBL579354

COC(=O)/C=C/c1cccc(C(C)C)c1C(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.54
ALDH1A1 P00352 5/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TYR P14679 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
NFE2L2 Q16236 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13299432 0.86 KDM4E (0.47) KDM4EALDH1A1MAPTMEN1TP53
SCHEMBL15512 0.84 KDM4E (0.47) KDM4EMAPTMEN1KMT2ACA12
SCHEMBL1173259 0.83 KDM4E (0.66) KDM4EMAPTCYP1A2HPGDKMT2A
SCHEMBL28528223 0.77 ALDH1A1 (0.40) KDM4EALDH1A1MAPTMEN1TP53
SCHEMBL24159780 0.76 ALDH1A1 (0.47) KDM4EALDH1A1MAPTMEN1TP53
SCHEMBL69522 0.76 ALDH1A1 (0.58) KDM4EALDH1A1MAPTMEN1TP53
SCHEMBL10438847 0.76 ALDH1A1 (0.58) KDM4EALDH1A1MAPTMEN1TP53
SCHEMBL11061667 0.75 ALDH1A1 (0.56) KDM4EALDH1A1MAPTMEN1TP53
SCHEMBL17695795 0.73 KEAP1 (0.43) NFE2L2
SCHEMBL156609 0.73 ALDH1A1 (0.48) KDM4EALDH1A1MAPTMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119015394-A Sulfur-containing compound preparation, and preparation method and application thereof 上海优斐斯生物科技有限公司 2024-11-26 CN claimed
US-20240374492-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2024-11-14 US claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN claimed
WO-2023009315-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2023-02-02 WO claimed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO claimed
CN-112914020-A Aqueous clear oil-in-water emulsions containing emulsified carotenoids 巴斯夫欧洲公司 2021-06-08 CN claimed
EP-2874507-B1 AQUEOUS TRANSPARENT OIL-IN-WATER EMULSION COMPRISING AN EMULSIFIED CAROTENOID BASF SE (DE) 2020-12-30 EP claimed
EP-2485807-B1 SUN-CARE COMPOSITIONS ISP INVESTMENTS LLC (US) 2019-07-03 EP claimed
EP-1595936-A1 ANTIOXIDATIVE COMPOSITION AND COMPOSITION FOR EXTERNAL USE MITSUBISHI CORPORATION (JP) 2005-11-16 EP claimed
US-20050249689-A1 Personal care compositions with enhanced properties, method of manufacture, and method of use thereof MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-10 US claimed
US-20050249690-A1 Personal care compositions with enhanced properties, method of manufacture, and method of use thereof MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-10 US claimed
EP-1107728-B1 COSMETIC COMPOSITIONS FOR SOLAR PROTECTION AND USES OREAL (FR) 2004-04-28 EP claimed
EP-1002523-B1 Cosmetic sunscreening compositions OREAL (FR) 2004-03-03 EP claimed
US-20040028642-A1 Cosmetic composition comprising an extract of emblica officinalis and methods of using same L'OREAL S.A. (FR) 2004-02-12 US claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
US-6409999-B2 Synergistically UV-photoprotecting benzotriazole-substituted silicon/cinnamic acid compositions SOCIETE L'OREAL (FR) 2002-06-25 US claimed
US-20010041167-A1 Synergistically UV-photoprotecting benzotriazole-substituted silicon/cinnamic acid compositions SOCIETE L'OREAL S.A. (FR) 2001-11-15 US claimed
US-6143282-A TOPICAL APPLYING SOCIETE L'OREAL S.A. (FR) 2000-11-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010041167-A1 Synergistically UV-photoprotecting benzotriazole-substituted silicon/cinnamic acid compositions SUCLG1, ARNT, BPTF KDM4E 3272/4885ALDH1A1 637/4885MAPT 999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.