Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 13/20 | 0.43 |
| ▸ | TP53 | P04637 | 6/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847524 | 0.87 | MDM2 (0.35) | MDM2TP53CCR1 | |
| SCHEMBL6847520 | 0.87 | MDM2 (0.35) | MDM2TP53CCR1 | |
| SCHEMBL15972924 | 0.73 | MDM2 (0.77) | MDM2TP53 | |
| SCHEMBL15972872 | 0.73 | MDM2 (0.77) | MDM2TP53 | |
| SCHEMBL15973241 | 0.73 | MDM2 (0.77) | MDM2TP53 | |
| SCHEMBL15972682 | 0.73 | MDM2 (0.77) | MDM2TP53 | |
| SCHEMBL9669500 | 0.70 | MDM2 (0.43) | MDM2TP53CCR1GPBAR1 | |
| SCHEMBL5746150 | 0.62 | LMNA (0.43) | MDM2TP53CCR1 | |
| SCHEMBL5747158 | 0.62 | HTT (0.52) | MDM2SMN1; SMN2 | |
| SCHEMBL5747156 | 0.62 | HTT (0.52) | MDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |