Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847520 | 1.00 | MDM2 (0.35) | MDM2AVPR1ACCR1ANPEPTP53 | |
| Hydroxyamine SCHEMBL5793570 | 0.87 | MDM2 (0.43) | MDM2CCR1TP53 | |
| SCHEMBL5746150 | 0.76 | LMNA (0.43) | MDM2AVPR1ACCR1ANPEPTP53 | |
| SCHEMBL5746146 | 0.76 | LMNA (0.43) | MDM2AVPR1ACCR1ANPEPTP53 | |
| SCHEMBL5747229 | 0.64 | KMT2A (0.53) | ANPEP | |
| SCHEMBL5747156 | 0.63 | HTT (0.52) | MDM2 | |
| SCHEMBL5747158 | 0.63 | HTT (0.52) | MDM2 | |
| SCHEMBL5747163 | 0.63 | HTT (0.52) | MDM2 | |
| SCHEMBL15972682 | 0.63 | MDM2 (0.77) | MDM2TP53 | |
| SCHEMBL15972924 | 0.63 | MDM2 (0.77) | MDM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |