Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 6/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795554 | 0.85 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1PDE1CGUSBCACNA1C | |
| SCHEMBL5767662 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1L3MBTL1LMNAMAPTALOX12 | |
| SCHEMBL5765770 | 0.76 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1PDE1CGUSBCACNA1C | |
| SCHEMBL5767262 | 0.76 | MAPK1 (0.44) | ALDH1A1GUSBLMNAMAPTALOX12 | |
| SCHEMBL5763392 | 0.75 | HTT (0.50) | ALDH1A1L3MBTL1GUSBLMNAMAPT | |
| SCHEMBL5766857 | 0.75 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1LMNAMAPTALOX12 | |
| SCHEMBL5766592 | 0.74 | GAA (0.46) | ALDH1A1L3MBTL1GUSBLMNAMAPT | |
| SCHEMBL5765442 | 0.74 | CACNA1C (0.44) | ALDH1A1CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL5766636 | 0.73 | SMN1; SMN2 (0.62) | ALDH1A1L3MBTL1LMNAADORA3MAPT | |
| SCHEMBL5794209 | 0.73 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAMAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116390-A1 | Hepatitis c virus inhibitors | LG LIFE SCIENCES LTD. (KR) | 2006-06-01 | — | — | US | disclosed |
| EP-1633725-A1 | HEPATITIS C VIRUS INHIBITORS | LG Life Sciences Ltd. (KR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004111013-A1 | HEPATITIS C VIRUS INHIBITORS | LG LIFE SCIENCES LTD. (KR) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116390-A1 | Hepatitis c virus inhibitors | HAVCR2, LIPC, FABP1 | ALDH1A1 1058/4885L3MBTL1 4120/4885PDE1C 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.