SCHEMBL7732791

SCHEMBL7732791

O=C1NC(=O)C(C(Br)Br)N1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
RGS12 O14924 1/20 0.33
BACE1 P56817 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7823880 0.81 TSHR (0.39) TSHRRGS12BACE1TDP1
SCHEMBL16597503 0.75 TSHR (0.48) TSHRRGS12BACE1TDP1
SCHEMBL98976 0.75 TSHR (0.48) TSHRRGS12BACE1TDP1
SCHEMBL6312105 0.75 TSHR (0.42) TSHRRGS12BACE1TDP1
SCHEMBL9402162 0.73 TSHR (0.46) TSHRRGS12BACE1TDP1
SCHEMBL9402143 0.71 TSHR (0.44) TSHRRGS12BACE1TDP1
SCHEMBL9828518 0.70 TSHR (0.43) TSHRRGS12BACE1
SCHEMBL9467064 0.70 TSHR (0.43) TSHRRGS12BACE1
SCHEMBL1168843 0.70 TSHR (0.43) TSHRRGS12BACE1
SCHEMBL498235 0.69 TSHR (0.41) TSHRBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10232678-B2 Stabilizer bar with rubber bush and method for producing same NHK SPRING CO., LTD. (JP) 2019-03-19 US disclosed
EP-3135512-A1 STABILIZER BAR WITH RUBBER BUSH AND METHOD FOR PRODUCING SAME NHK Spring Co., Ltd. (JP) 2017-03-01 EP disclosed
US-20170043641-A1 STABILIZER BAR WITH RUBBER BUSH AND METHOD FOR PRODUCING SAME NHK SPRING CO., LTD. (JP) 2017-02-16 US disclosed
CN-104903298-A Process for producing halohydantoin compounds NIPPOH CHEMICALS 2015-09-09 CN disclosed
EP-2650150-B1 BUSH- AND BRACKET-INTEGRATED STABILIZER BAR NHK SPRING CO LTD (JP) 2015-09-02 EP disclosed
CN-104884439-A Production method for halohydrantoin compound and halohydrantoin compound NIPPOH CHEMICALS 2015-09-02 CN disclosed
CN-104854095-A PRODUCTION METHOD AND PRODUCTION DEVICE FOR HALO-HYDANTOIN COMPOUND, REUSE SYSTEM, AND HALO-HYDANTOIN COMPOUND NIPPOH CHEMICALS 2015-08-19 CN disclosed
US-8613460-B2 Bush- and bracket-integrated stabilizer bar NHK SPRING CO., LTD. (JP) 2013-12-24 US disclosed
US-20130270787-A1 BUSH- AND BRACKET-INTEGRATED STABILIZER BAR NHK SPRING CO., LTD. (JP) 2013-10-17 US disclosed
EP-2650150-A1 BUSH- AND BRACKET-INTEGRATED STABILIZER BAR NHK Spring Co., Ltd. (JP) 2013-10-16 EP disclosed
US-6407076-B1 ANTIISCHEMIC, ANTILIPOLYTIC, ANTICONVULSANT AND HYPOTENSIVE AGENTS; CARDIOVASCULAR AND NERVOUS SYSTEM DISORDERS; ATHEROSCLEROSIS SMITHKLINE BEECHAM CORPORATION 2002-06-18 US disclosed
US-6106853-A TREATING GASES OR VAPOR POLLUTANTS AND NEUTRALIZATION BROMINE COMPOUDS, CHLORINE COMPOUNDS, ALCOHOL OR ACETIC ACID COX JAMES P (US) 2000-08-22 US disclosed
EP-1027363-A2 ADENOSINE A1-RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2000-08-16 EP disclosed
WO-1999024450-A2 ADENSINE A1 RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 1999-05-20 WO disclosed
WO-1994014524-A1 DEVOLATILIZING AND STABILIZING VAPOROUS POLLUTANTS COX JAMES P (US) 1994-07-07 WO disclosed
US-4119535-A Method of sanitizing a volume of water in conjunction with chlorine KORHUMEL INC., A CORP OF IL 1978-10-10 US disclosed