Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837823 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1CHRM2OPRM1DDB1 | |
| SCHEMBL4839855 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1CHRM2OPRM1DDB1 | |
| SCHEMBL14263755 | 0.80 | NPSR1 (0.34) | NPSR1ALDH1A1LMNAHTTKDM4E | |
| SCHEMBL14263754 | 0.80 | NPSR1 (0.34) | NPSR1ALDH1A1LMNAHTTKDM4E | |
| SCHEMBL4833881 | 0.78 | NPSR1 (0.43) | NPSR1ALDH1A1LMNAHTTALOX15 | |
| SCHEMBL5791168 | 0.78 | NPSR1 (0.43) | NPSR1ALDH1A1LMNAHTTALOX15 | |
| SCHEMBL4837879 | 0.78 | NPSR1 (0.43) | NPSR1ALDH1A1LMNAHTTALOX15 | |
| SCHEMBL8313412 | 0.77 | ALDH1A1 (0.36) | NPSR1ALDH1A1CHRM2OPRM1DDB1 | |
| SCHEMBL4845001 | 0.77 | ALDH1A1 (0.36) | NPSR1ALDH1A1CHRM2OPRM1DDB1 | |
| SCHEMBL8313398 | 0.76 | ALDH1A1 (0.42) | NPSR1ALDH1A1TDP1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |