Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.41 |
| ▸ | GPR4 | P46093 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 3/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815642 | 0.88 | CTSK (0.40) | CTSKGPR4ATMHRH3CTSS | |
| SCHEMBL5793393 | 0.85 | CTSK (0.41) | CTSKGPR4 | |
| SCHEMBL5791444 | 0.84 | CTSK (0.40) | CTSKGPR4 | |
| SCHEMBL5794663 | 0.83 | CTSK (0.39) | CTSKGPR4HRH3CTSBCTSS | |
| SCHEMBL5791034 | 0.83 | CTSK (0.42) | CTSKGPR4CTSLCTSBCTSS | |
| SCHEMBL5792592 | 0.82 | MAOB (0.39) | CTSK | |
| SCHEMBL5792575 | 0.82 | CTSK (0.44) | CTSKGPR4CTSLCTSBCTSS | |
| SCHEMBL5791906 | 0.79 | MAOB (0.40) | CTSK | |
| SCHEMBL5791897 | 0.79 | MAOB (0.41) | CTSK | |
| SCHEMBL5793788 | 0.78 | CTSK (0.38) | CTSKGPR4HRH3KCNH2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |