Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310574 | 0.80 | VCAM1 (0.58) | HPGDALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL2772078 | 0.79 | KMT2A (0.54) | HPGDALDH1A1NPSR1KMT2AMAPT | |
| SCHEMBL498267 | 0.78 | KDM4E (0.54) | HPGDALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL13011426 | 0.77 | VCAM1 (0.53) | HPGDALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL30445111 | 0.77 | ALDH1A1 (0.65) | HPGDALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL7566531 | 0.77 | ALDH1A1 (0.65) | HPGDALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL268414 | 0.77 | TDP1 (0.62) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2314995 | 0.77 | VCAM1 (0.50) | HPGDALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL30863327 | 0.76 | VCAM1 (0.66) | HPGDALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL1316996 | 0.76 | KDM4E (0.55) | ALDH1A1NPSR1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012310-A2 | CARBAZOLE DERIVATIVES FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |