Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198679 | 0.87 | MAOB (0.64) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL9058391 | 0.87 | MAOB (0.64) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL3277849 | 0.80 | MEN1 (0.68) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL30667838 | 0.78 | SHMT2 (0.57) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL17792752 | 0.77 | SHMT2 (1.00) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL6756877 | 0.76 | MTNR1A (0.52) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL432850 | 0.75 | ALOX5 (0.71) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL10470600 | 0.75 | ALOX5 (0.71) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL266611 | 0.75 | MTNR1A (0.53) | MAPTMEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL10334868 | 0.75 | ALOX5 (0.56) | MAPTMEN1KMT2AHTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006040646-A1 | BENZIMIDAZOLE OR INDOLE AMIDES AS INHIBITORS OF PIN1 | PFIZER, INC. (US) | 2006-04-20 | — | — | WO | disclosed |