Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807088 | 0.84 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL5798466 | 0.82 | KMT2A (0.46) | L3MBTL1ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL11888752 | 0.81 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1POLBHPGDKMT2A | |
| SCHEMBL5796806 | 0.81 | KMT2A (0.45) | L3MBTL1ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL5798883 | 0.80 | KMT2A (0.44) | L3MBTL1ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL10478884 | 0.80 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL5795479 | 0.79 | HSD11B1 (0.46) | POLBMAPTKDM4EPTGDR2HCRTR1 | |
| SCHEMBL5795471 | 0.79 | HSD11B1 (0.46) | POLBMAPTKDM4EPTGDR2HCRTR1 | |
| SCHEMBL11947869 | 0.77 | ALDH1A1 (0.59) | L3MBTL1ALDH1A1POLBHPGDMAPT | |
| SCHEMBL5798827 | 0.77 | HSD11B1 (0.40) | ALDH1A1KMT2AMAPTKDM4EHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030211-A2 | ACYCLIC SULPHONAMIDES | VERNALIS (R & D) LIMITED (GB) | 2006-03-23 | — | — | WO | disclosed |