Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.64 |
| ▸ | PPARA | Q07869 | 8/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248386 | 0.88 | PPARG (0.61) | PPARGPPARACYP1A2CYP2C19CYP4F2 | |
| SCHEMBL11215916 | 0.88 | PPARG (0.61) | PPARGPPARACYP1A2CYP2C19CYP4F2 | |
| SCHEMBL8591991 | 0.86 | CYP1A2 (0.51) | PPARGPPARACYP1A2CYP2C19PPARD | |
| SCHEMBL1550516 | 0.85 | PPARA (0.49) | PPARGPPARACYP1A2CYP2C19PPARD | |
| SCHEMBL6081046 | 0.84 | PPARA (0.67) | PPARGPPARACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5795465 | 0.83 | ALDH1A1 (0.56) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL3840661 | 0.83 | PPARG (0.71) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL3848011 | 0.82 | PPARA (0.69) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL4034371 | 0.82 | PPARA (0.69) | PPARGPPARACYP1A2CYP2C19CYP4F2 | |
| SCHEMBL5561664 | 0.82 | CYP1A2 (0.55) | PPARGPPARACYP1A2CYP2C19PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006035157-A2 | SUBSTITUTED N-(BENZYL)PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME AS PPAR LIGANDS IN THE TREATMENT OF LIPID AND/OR GLUCIDIC DISORDERS | GENFIT (FR) | 2006-04-06 | — | — | WO | disclosed |