Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.61 |
| ▸ | PPARA | Q07869 | 10/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795203 | 0.88 | PPARG (0.64) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL11215916 | 0.85 | PPARG (0.61) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL6543605 | 0.85 | PPARA (0.48) | PPARGPPARACYP1A2CYP2C19 | |
| SCHEMBL6543477 | 0.83 | PPARA (0.66) | PPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL3848011 | 0.82 | PPARA (0.69) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL7906877 | 0.81 | PPARA (0.68) | PPARGPPARAPPARDCYP1A2CYP2C19 | |
| SCHEMBL5795465 | 0.81 | ALDH1A1 (0.56) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL3840661 | 0.81 | PPARG (0.71) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL6685564 | 0.80 | EPHX1 (0.52) | — | |
| SCHEMBL2439451 | 0.80 | PPARA (0.74) | PPARGPPARACYP4F2CYP4A11PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |