Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364536 | 0.82 | KDM4E (0.45) | NMUR2MEN1CYP3A4KMT2AKDM4E | |
| SCHEMBL2428081 | 0.79 | NMUR2 (0.47) | NMUR2MEN1CYP3A4KMT2AKDM4E | |
| SCHEMBL290080 | 0.78 | NMUR2 (0.71) | NMUR2MEN1CYP3A4KMT2AKDM4E | |
| SCHEMBL31675811 | 0.78 | NMUR2 (0.71) | NMUR2MEN1CYP3A4KMT2AKDM4E | |
| SCHEMBL7047704 | 0.77 | IKBKB (0.59) | NMUR2MEN1CYP3A4KMT2AKDM4E | |
| SCHEMBL1423153 | 0.75 | NMUR2 (0.54) | NMUR2MEN1CYP3A4KMT2AKDM4E | |
| SCHEMBL13049683 | 0.74 | AKR1C3 (0.46) | NMUR2MEN1CYP3A4KMT2AKDM4E | |
| SCHEMBL5795794 | 0.73 | ABCB1 (0.51) | MEN1CYP3A4KMT2AKDM4EALOX15 | |
| SCHEMBL7354775 | 0.72 | NQO1 (0.75) | MEN1CYP3A4KMT2AMAPK1TP53 | |
| SCHEMBL15328698 | 0.71 | CA12 (0.52) | NMUR2MEN1CYP3A4KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006042007-A2 | CHROMENONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | claimed |
| WO-2006042007-A2 | CHROMENONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |