Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.59 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428081 | 0.85 | NMUR2 (0.47) | IKBKBPTPN1KDM4EMEN1ALDH1A1 | |
| SCHEMBL623887 | 0.83 | VKORC1 (0.59) | IKBKBVKORC1PTPN1CYP19A1KDM4E | |
| SCHEMBL16924700 | 0.79 | VKORC1 (0.63) | IKBKBVKORC1PDE4DPTPN1NUDT1 | |
| SCHEMBL2364536 | 0.78 | KDM4E (0.45) | KDM4EMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL5795210 | 0.77 | NMUR2 (0.47) | PTPN1KDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL290080 | 0.76 | NMUR2 (0.71) | KDM4EMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL31675811 | 0.76 | NMUR2 (0.71) | KDM4EMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL25196944 | 0.75 | IKBKB (0.72) | IKBKBVKORC1PTPN1NUDT1RELA | |
| SCHEMBL7047705 | 0.75 | CYP3A4 (0.59) | IKBKBVKORC1PDE4DPTPN1NUDT1 | |
| SCHEMBL15328698 | 0.75 | CA12 (0.52) | KDM4EMEN1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114796194-A | Application of DA adduct derived from Morus plant in preparation of beta-G inhibitor | 澳门大学 | 2022-07-29 | — | — | CN | claimed |
| CN-110872267-A | Compound extracted from paper mulberry and application of compound in preparation of protein tyrosine phosphatase 1B inhibitor | 复旦大学 | 2020-03-10 | — | — | CN | claimed |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | UNIGEN, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| CN-115950978-A | Method for identifying flavonol novel compound in epimedium secondary metabolic pathway | 重庆市中药研究院 | 2023-04-11 | — | — | CN | disclosed |
| CN-115364089-A | Application of sanggenon C in preparing medicine for treating glioblastoma | 西南大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-114796194-A | Application of DA adduct derived from Morus plant in preparation of beta-G inhibitor | 澳门大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-110872267-B | Compound extracted from paper mulberry and application of compound in preparation of protein tyrosine phosphatase 1B inhibitor | 复旦大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-109207450-B | Flavonoid isopentenyl transferase gene and application thereof | 中国农业科学院北京畜牧兽医研究所 | 2022-04-15 | — | — | CN | disclosed |
| US-11123393-B2 | Compositions and methods for joint health | UNIGEN, INC. (US) | 2021-09-21 | — | — | US | disclosed |
| CN-110872267-A | Compound extracted from paper mulberry and application of compound in preparation of protein tyrosine phosphatase 1B inhibitor | 复旦大学 | 2020-03-10 | — | — | CN | disclosed |
| EP-3010928-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | Unigen, Inc. (US) | 2016-04-27 | — | — | EP | disclosed |
| US-20160067296-A1 | Compositions and Methods for Joint Health | UNIGEN, INC. (US) | 2016-03-10 | — | — | US | disclosed |
| US-20150072953-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | UNIGEN, INC. | 2015-03-12 | — | — | US | disclosed |
| WO-2014204866-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | UNIGEN, INC. (US) | 2014-12-24 | — | — | WO | disclosed |
| WO-2003013554-A2 | AROMATASE INHIBITORS FROM BROUSSONETIA PAPYRIFERA | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-02-20 | — | — | WO | disclosed |
| US-6399579-B1 | SOLVENT EXTRACTION; PLANT EXTRACTS | HAUSER, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2002013842-A1 | COMPOSITIONS COMPRISING ICARISIDE I AND ANHYDROICARITIN AND METHODS FOR MAKING THE SAME | HAUSER, INC. (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150072953-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | PTGES, PTGES3, PTGES2 | IKBKB 174/4885VKORC1 269/4885PDE4D 1843/4885 |
| US-11123393-B2 | Compositions and methods for joint health | PTGES, PTGES3, PTGES2 | IKBKB 174/4885VKORC1 269/4885PDE4D 1843/4885 |
| US-20160067296-A1 | Compositions and Methods for Joint Health | PTGES, PTGES3, PTGES2 | IKBKB 174/4885VKORC1 269/4885PDE4D 1843/4885 |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | PTGES, PTGES3, PTGES2 | IKBKB 174/4885VKORC1 269/4885PDE4D 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.