Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205565 | 0.75 | MAOA (0.65) | KDM4EALDH1A1NPC1CA1CA2 | |
| SCHEMBL5795210 | 0.73 | NMUR2 (0.47) | ABCB1KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL29128892 | 0.72 | KDM4E (0.69) | KDM4EALDH1A1CYP3A4HSD17B10TSHR | |
| SCHEMBL30558215 | 0.72 | ABCG2 (0.66) | KDM4EALDH1A1CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL29080548 | 0.72 | ABCG2 (0.66) | KDM4EALDH1A1CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL29080541 | 0.71 | ABCG2 (0.52) | ABCB1KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL27250718 | 0.71 | MAPT (0.70) | ABCB1KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL10769734 | 0.71 | ABCG2 (0.72) | KDM4EALDH1A1CYP3A4HSD17B10TSHR | |
| SCHEMBL30558252 | 0.70 | ABCG2 (0.67) | KDM4EALDH1A1CYP3A4HSD17B10TSHR | |
| SCHEMBL29080543 | 0.70 | ABCG2 (0.67) | KDM4EALDH1A1CYP3A4HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006042007-A2 | CHROMENONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |