SCHEMBL5795352

SCHEMBL5795352

COC(=O)Cc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
MAPT P10636 4/20 0.44
CYP19A1 P11511 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 2/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPK1 P28482 2/20 0.44
HSD17B10 Q99714 2/20 0.44
ALOX15 P16050 1/20 0.44
KMT2A Q03164 1/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2C9 P11712 1/20 0.44
NFKB1 P19838 1/20 0.44
BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2240555 0.88 AKR1C3 (0.42) AKR1C3L3MBTL1MAPTGAATSHR
SCHEMBL2238486 0.88 KDM4E (0.50) AKR1C3L3MBTL1MAPTKDM4EMAPK1
SCHEMBL11461546 0.86 ABCB11 (0.57) MAPTGAALMNA
SCHEMBL3916488 0.84 FOLH1 (0.50) GAATSHRKDM4EMAPK1HSD17B10
SCHEMBL11460505 0.84 KDM4E (0.40) AKR1C3L3MBTL1MAPTGAAKDM4E
SCHEMBL27627533 0.84 CFD (0.46) AKR1C3L3MBTL1MAPTGAAKDM4E
SCHEMBL9844983 0.84 ALDH1A1 (0.53) AKR1C3L3MBTL1MAPTCYP19A1GAA
SCHEMBL7043694 0.82 ALDH1A1 (0.61) L3MBTL1MAPTTSHRKDM4EMAPK1
SCHEMBL9277399 0.81 AKR1C3 (0.52) AKR1C3L3MBTL1MAPTCYP19A1GAA
SCHEMBL1122035 0.81 AKR1C3 (0.52) AKR1C3L3MBTL1MAPTCYP19A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107876092-B Application of titanium catalyst with cyclic structure as reaction catalyst for synthesizing benzyl carbonate or diphenyl carbonate by ester exchange 华东理工大学 2023-01-10 CN claimed
US-7396885-B2 Photo-setting and thermosetting resin composition, process for preparing plugged-through-hole printed wiring board and plugged-through-hole printed wiring board SAN-EI KAGAKU CO., LTD. (JP) 2008-07-08 US disclosed
WO-2006051312-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2006-05-18 WO disclosed