Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796627 | 0.92 | KIF11 (0.46) | KIF11FTOMEN1KMT2AATM | |
| SCHEMBL5798874 | 0.85 | KIF11 (0.45) | KIF11FTOMEN1KMT2AATM | |
| SCHEMBL5796618 | 0.85 | KIF11 (0.45) | KIF11FTOMEN1KMT2AATM | |
| SCHEMBL5798774 | 0.84 | PARP14 (0.43) | KIF11FTOMEN1KMT2AMAPT | |
| SCHEMBL1306405 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL12113454 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1306406 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL5798821 | 0.82 | MAPT (0.43) | KIF11FTOMEN1KMT2AATM | |
| SCHEMBL5798816 | 0.82 | MAPT (0.43) | KIF11FTOMEN1KMT2AATM | |
| SCHEMBL5813698 | 0.82 | NOTUM (0.39) | KIF11FTOMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |